Wednesday, September 5, 2012

The weight loss drug Orlistat (Xenical or Alli) never enabled significant weight loss and always caused nasty side effects. But, once again, the dieter is blamed for weight loss failure…this time blamed for “thinking” the drug will not work.


 

The weight loss drug is Orlistat.  You may know it as Xenical or Alli. It has been available by prescription since 1999 and over the counter since 2007.  A dieter is to take the medication at meals that contain fat.  The drug blocks the absorption of fat and allows it to pass undigested through the intestines.  The fat, grease, oil passes through the intestines…and out your back end….Side effects include steatorrhea (oily loose stools), excessive gas/flatulence, fecal incontinence, as well as frequent and urgent bowel movements.  Yep.  The average weight loss taking Alli is 3-5 pounds/YEAR.

Weight loss is supposed to occur from not absorbing the fat calories and from behavioral modification.  Embarrassing stool “leaks” and major gas should teach a dieter to eat less fat…or else.

With that said, I’m embarrassed to report Dr. Hollywood and Dr. Ogden’s (University of Surrey) research presented in Liverpool this week.

The doctors interviewed 10 women who gained weight while taking the drug Orlistat for 18 months.  Although the women attributed their failure to lose weight to the mechanics of the drug and talked about other weight loss methods that did not work for them, the doctors had a very interesting “take” on their comments. 

Dr. Hollywood interpreted their weight gain as a “self fulfilling belief” that they would not lose weight. and went on to say that “unless we get the psychology right and change people’s beliefs about themselves, their eating and the way the drug works, this medication is often going to produce disappointing results.

So…the dieter is blamed for not losing weight while taking Orlistat…and in fact gaining weight.  It’s not the failure of the medication, it’s consumer failure. 

Truth be known, the reason people don't lose appreciable weight while taking Orlistat is that the drug DOES work...it does cause malabsorption of ingested fat.  Yes, the drug does what it is supposed to do, and dietary fat intake will cause nasty anal leakage of fat as well as gas and oily stools.  The modus operandi of the drug is two fold...malabsorb fat and cause behavioral modification.  In an effort to stop the embarrassment of leaking fat...people are supposed to eat less fat.  They should eat less fat and the fat they do consume should be malabsorbed.  Messy...but it should work for weight loss, right?  WRONG. 

Here’s where the doctors Hollywood and Ogden got it wrong….

The problem with Alli or Xenical is that they target fat intake.  The reality is that for over 60% of the population, weight issues are not caused by fat intake...they are caused by excess carbohydrate intake.  Over 60% of the population has the genes for metabolic syndrome with its characteristic over-release of the fat- gain hormone insulin in response to eating carbohydrate foods.

If the millions of people with insulin imbalance (I call this Metabolism B) dutifully pop their Orlistat...and avoid obvious high fat foods to avoid nasty anal fat leakage and gas, they will still consume carbohydrates.  Even healthy carbohydrates like whole grain breads, fresh fruit, legumes, fat free yogurt and milk cause blood sugar to rise and insulin to release.  Over 60% of the population becomes "fat" from over-processing carbohydrate due to an imbalance of the hormone insulin.

The medicine Orlistat can’t help this situation... this medicine will never solve the underlying  problem. 

We need to recognize "Metabolism B"(aka  metabolic syndrome).  Spread the word that most overweight people have insulin imbalance.   They WILL lose weight, keep it off, have energy, cut medication needs for blood sugar, cholesterol, blood pressure, and maintain excellent health following a lifestyle that matches their metabolic needs.

The lifestyle program written expressly for the millions with insulin imbalance (Metabolism B) is in The Metabolism Miracle.  Read more at www.themetabolismmiracle.com.
 





 
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Saturday, September 1, 2012

“Startling” Findings Reported in The Journal of Clinical Endocrinology and Metabolism


Taking Vitamin D supplements May Not Improve Heart Health

To which I reply  “No kidding.”

For over 30 years, I have worked closely with patients who have metabolic syndrome.  Metabolic Syndrome is a compilation of illnesses that occur in a “package”… including some or all of the following: midline adiposity, hypertension, elevated cholesterol (LDL), low HDL cholesterol, elevated triglycerides, elevated blood sugar.  At the root of metabolic syndrome is an imbalance of the fat gain hormone; insulin.
 For fifteen of those thirty years, I meticulously collected lab data on over 6000 patients whom I worked with regarding medical nutrition.  It has been many years since I realized the direct relationship between uncontrolled metabolic syndrome and low levels of Vitamin D.  Just as there is a causal relationship between insulin imbalance and metabolic syndrome, there is a direct relationship between uncontrolled metabolic syndrome (insulin imbalance) and Vitamin D deficiency.
 I also found the following to be true: Merely supplementing with Vitamin D to artificially “normalize” Vitamin D levels does nothing to improve heart health or improve CVD risk factors because…the underlying cause of the syndrome, insulin imbalance, is not corrected with Vitamin D. 
It’s like taking a statin, an antihypertensive medication and an oral hypoglycemic agent to artificially “normalize”cholesterol, hypertension, and blood sugar and thinking the medication will fix the underlying problem.Unfortunately, this is not the case.Stop the medication and cholesterol, blood pressure, and blood sugar rebound right back to elevated levels.The medications are not cures, they are Band-Aids.
Unless a person gets to the root of the underlying health problem and cuts out the “root”…the weed will continue to proliferate.  And so it goes with insulin imbalance and high cholesterol, triglycerides, blood pressure, blood sugar, midline fat, and now….low Vitamin D.
I am sure of the following:  When patients control their metabolic syndrome…...not by band-aiding their cholesterol, blood pressure, blood sugar, etc. with medications but through lifestyle changes that enable  them to normalize their labwork from within….their Vitamin D levels automatically rise ...without supplementation.
I've deduced that normalizing Vitamin D levels "artificially"...through Vitamin D supplementation...does nothing to improve metabolic syndrome.  So, supplements of Vitamin D are not going to improve CVD risk factors.  The real truth is: Normalizing insulin and thereby normalizing metabolic syndrome will normalize Vitamin D levels as well as improve cholesterol, midline adiposity, blood pressure, blood glucose and triglycerides.
It only makes sense.  Why would supplementing with Vitamin D help heart health and reduce CVD risk factors when the underlying and progressive metabolic syndrome remains intact?
 I may not have a research study published in the Journal of Clinical Endocrinology and Metabolism but I have worked in the laboratory of the “real world” for over 30 years with thousands of real people who have real diseases and need real answers.  Let’s be straight with them. 
Believe me when I tell you, most people don’t know what end is up with the flip flopping on issues that comes from major statements and pronouncements that come from medical associations  and research studies that are retracted a very short time later….
It’s time to get back to the basics of wellness and disease prevention and treat from within instead of adding Band-Aids on the outside.
 

September 1, 2012….Taking Vitamin D supplements May Not Improve Heart Health. No Kidding.


Stunning findings revealed in the Journal of Clinical Endocrinology and Metabolism

"Taking Vitamin D supplements May Not Improve Heart Health"
To which I say...."No Kidding".
 

 

For over 30 years, I have worked with patients with metabolic syndrome. For the past 15 of those thirty years, I have collected data on over 6000 patients.  I have found the following to be true with my patients who present with metabolic syndrome, pre diabetes, or type 2 diabetes.  Merely supplementing with Vitamin D to artificially “normalize” Vitamin D levels does nothing to improve heart health or improve CVD risk factors because…the underlying cause of the syndrome, insulin imbalance, is not corrected with Vitamin D.

Most of my patients with uncontrolled metabolic syndrome; having at least 4 of the following: elevated LDL cholesterol, low HDL, hypertension, hypertriglyceridemia, glucose intolerance, midline adiposity  had Vitamin D less than 40mg/dL.  I learned early on that there was a causative effect between uncontrolled metabolic syndrome and low Vitamin D.

For years now, I have seen the connection between uncontrolled metabolic syndrome, pre diabetes, type 2 diabetes and low levels of Vitamin D.  I am also sure of the following:  When these patients manage to control their metabolic syndrome…...not by band-aiding their cholesterol, blood pressure, blood sugar, etc. with medications but through lifestyle change that enable  them to normalize their labwork….their Vitamin D levels automatically rise ...without supplementation.

I've deduced that normalizing Vitamin D levels "artificially"...through Vitamin D supplementation...does nothing to improve metabolic syndrome.  So, supplements of Vitamin D are not going to improve CVD risk factors.  But...normalizing insulin and thereby normalizing metabolic abnormalities that cause aberrations in lab results will normalize Vitamin D levels as well as improve cholesterol, midline adiposity, blood pressure, blood glucose and triglycerides.

It only makes sense.  Why would supplementing with Vitamin D help heart health and reduce CVD risk factors when the underlying and progressive metabolic syndrome remains intact?